ABSTRACT
Infertility is a condition in which successful pregnancy has not occurred, despite normal intercourse over 12 months. The cause of female infertility is multifactorial. Ayurveda assures normal pregnancy by proper maintenance of Garbha Samgraha samagris and normalcy of mind. All the causes of female infertility come under the imbalance of Garbha Samgraha Samagri and mind factors. In this case report patient suffered from primary infertility since six years, after allopathic consultation came for ayurvedic treatment. From detailed history involvement of vitiated Vatha, Agnimandhya and stressful mind was noticed. She was treated with Chiruvilwadi kashayam, Dhanwantharam gulika, Jeerakarishtam, Kumaryasavam and Manasamithravatakam for one month. Took follicular study on next cycle and revealed post ovulatory status on 16th day of cycle. Advised Phalasarpis, Dhanwantharam Gulika and Manasamithravatakam for two weeks. Patient came with positive urine pregnancy test after one week of missed period. The line of treatment followed in this case was to maintain Agni, normalize Vatha and assure proper health to mind. During the second half of the cycle Garbhasthapana medicines were administered. Patient took Dhanwantharam gulika and phalasarpis throughout the first trimester along with regular ante natal check up. Continued Dhanwantharam gulika up to 36 weeks and started Sukhaprasavagritham upto delivery from 36 weeks onwards. She delivered a female baby on 06.05.2018.
ABSTRACT
Children with the clinical features of Chronic Tonsillitis coming under the age group 3-12 years were included in the study. The patients were randomly allocated in to the study group and control group using simple random sampling technique. In the study group the dose of Varabrihatyadi Kashaya was fixed as follows, in the age group 3-6 years: 10ml bd before food, in the age group 6-9 years: 20ml bd before food, in the age group 9-12 years: 30ml bd before food. Sarapunkha lepa was applied around the neck where enlarged lymph nodes were found. Frequency of paste was fixed as two times daily and at each time, it is kept until it becomes dry. At the same time those in the control group were subjected to external application of Sarapunkha lepa only. Both the groups were followed for a period of 1 month after the scheduled course of intervention. Routine blood investigations were also carried out before and after the study. The data were analyzed using the most appropriate statistical tests. Significant changes were obtained in the clinical parameters in the study group used for assessment such as recurrent attacks of sore throat, pain in the throat, pain on swallowing, difficulty in swallowing, halitosis, mouth breathing, hoarseness of voice, chocking spells at night, size of the tonsil, congestion of pillars, oedema of the uvula, deviation of the uvula and lymph node enlargement. There was a significant change in the routine blood investigations also. Moreover the trial drug sustained its potential action even during the follow up period. The effect of control drug was insignificant. The final evaluation proved that combination of Varabhrihathyadi Kashaya and Sarapunkha lepa was effective in reducing the signs and symptoms of Chronic Tonsillitis in children of 3-12 yrs age group.
ABSTRACT
Introduction: Stroke is a global health problem. In this study we evaluated the risk factors, clinical features and their correlation with Magnetic Resonance Imaging (MRI) brain including Magnetic Resonance Angiogram (MRA) and Carotid Verteberal (CV) Doppler findings in patients presenting with acute ischemic stroke. Material and methods: Seventy five patients of the age group 20 to 80 years admitted with acute ischemic stroke were enrolled for the study. A detailed history, clinical examination and blood investigations were done. MRI, MRA and CV Doppler were done in all patients. Serum Homocysteine levels and Anti-nuclear antibody assay (ANA) by Immunofluorescence (IF) were done in selected patients. Statistical analysis was done using SSPS version 16.0 for microsoft windows. Results: In this study, there were more males than females. The mean age was 59 years. Young stroke population (<40 years) was 5%. Anterior circulation was predominantly involved than posterior circulation. Right Middle Cerebral Artery was the most common artery involved. There was positive correlation for clinical presentation and area of infarct and for areas of infarct and the vessels involved. Most common clinical presentations were weakness and slurring of speech. There were 3% intracranial anomalies. 56% had significantly elevated levels of homocysteine. 24% had ANA- IF positivity. Recurrence of stroke was seen in 17%; National Institute of Health Stroke Scale (NIHSS) score was higher in patients with recurrent stroke and right hemisphere infarcts. Conclusion: There was positive correlation for clinical presentation and area of infarct and for areas of infarct and the vessels involved.
ABSTRACT
Drought-tolerant cultivars and their phytochemical composition, which has a role in providing drought tolerance are gaining importance. In this study, rice bran oil and semi-purified oryzanol (SPO) obtained from five rice (Oryza sativa L.) cultivars, namely P1401 and PB1 (drought-susceptible) and N22, PNR381 and APO (drought-tolerant) were analyzed for the γ-oryzanol content, an antioxidant present in considerable amount in the rice bran. The higher level of γ-oryzanol and its antioxidant activity was observed in drought-tolerant cultivars (N22, PNR381 and APO) as compared to drought-susceptible (PB1 and P1401), suggesting the role of γ-oryzanol in drought tolerance, as antioxidants are known to play an important role by scavenging free radicals. The total antioxidant activity of γ-oryzanol might be attributed to 24-methylene cycloartanyl ferulate, a major component of γ-oryzanol. By enhancing the level of active oryzanol components identified in this study by genetic and molecular means could impart increased drought tolerance.